Our Research Goal and Topics


Catalytic transformation of aliphatic and unsaturated systems into value-added structures

Our research goal is to develop synthetic methods based on the understanding of reactivities of catalytic manifolds.
We investigate metal catalyzed inert bond activation, annulation, cycloaddition and hydrofunctionalization reactions.

Compounds

Annulative transformation of (het)arenes using hypervalent iodine compounds
Nat. Commun. 2022, 13, 2421; base-promoted Minisci-type annulation of simple azines
Org. Lett. 2019, 21, 7004; annulation of arenes via nondirected electrophilic C–H activation
Angew. Chem. Int. Ed. 2017, 56, 5007; annulative approach for triphenylenes via C–H arylation
Chem. Commun. 2017, 53, 10394; annulative functionalization of quinazoliones via C–H arylation


Transformations of unsaturated molecules: mechanistic study & identification of catalytic species

Commun. Chem. 2022, 5, 13; Ni-catalyzed reductive hydroacylation of alkynes to access enones
J. Org. Chem. 2021, 86, 9328; Ni-catalyzed [2+2+2] cycloaddition to access multi-substituted pyridines
J. Am. Chem. Soc. 2017, 139, 12121; NiAAC click chemistry to selectively access 1,5-disubstituted triazoles


Synthesis and applications of organosulfur compounds and fluorosulfates for value-added products

Org. Lett. 2021, 23, 2766; synthetic approach to 18F-labelled sulfamoyl fluorides via isotope exchange
Org. Lett. 2020, 22, 5511; nucleophilic fluorination of aryl imidazylates and synthesis of aryl fluorosulfates


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Prof. Sung You Hong | Ulsan National Institute of Science and Technology (UNIST)
email: syhong@unist.ac.kr