Our Research Goal and Topics

Transformation of Simple Chemicals Into Value-Added Compounds

We are keen on the development of synthetic methods based on the mechanistic understanding.

Nickel catalysis: reactivity study, mechanistic investigations & identification of active catalytic species
JACS Au 2024, 4, 1646; nickel-catalyzed borylation of aryl fluorosulfates and identification of nickel(II) species
J. Org. Chem. 
2021, 86, 9328; nickel-catalyzed [2+2+2]-cycloaddition to access multi-substituted pyridines
J. Am. Chem. Soc. 2017, 139, 12121; NiAAC to access 1,5-disubstituted triazoles under ambient conditions

SuFEx chemistry: iterative synthesis and applications of oligosulfates and studies on synthetic methods
Nat. Commun. 2024, 15, 3381; homologation approach for the synthesis of sequence-controlled oligosulfates
Org. Lett. 
2021, 23, 2766; direct synthetic approach to 18F-labelled sulfamoyl fluorides via isotope exchange
Org. Lett. 2020, 22, 5511; nucleophilic fluorination of aryl imidazylates and synthesis of aryl fluorosulfates

Annulative chemistry: multiple bond formation to access fused cyclic structures including triphenylenes
Nat. Commun. 2022, 13, 2421; base-promoted Minisci-type annulation reactions of azines for N-doped PAHs
Org. Lett. 2019, 21, 7004; annulation of simple arenes via non-directed electrophilic two-fold C–H activation
Angew. Chem. Int. Ed. 2017, 56, 5007; annulative approach for substituted triphenylenes via two-fold arylation

Prof. Sung You Hong | Ulsan National Institute of Science and Technology (UNIST)
email: syhong@unist.ac.kr